A peaceful Saturday evening in Arizona turned into a nationwide emergency within hours, as an 84-year-old family matriarch vanished without explanation. For Savannah Guthrie, longtime co-anchor of Today, February 2026 has become defined by a deeply personal ordeal. What initially appeared to be a missing persons case has since evolved into a complex federal investigation centered on the possibility of abduction. As of February 23, the disappearance of Nancy Guthrie from her Tucson residence has revealed troubling details that have shaken both her family and the surrounding community.

In the days following Nancy’s disappearance, the Guthrie family has largely stepped out of public view, choosing privacy in order to focus on search efforts. That silence was briefly interrupted when Savannah’s sister, Annie Guthrie, and her husband, Tommaso Cioni, were seen in public for the first time since the investigation began. Photographs taken in Tucson showed a visibly strained couple attempting to move through daily life while under intense media attention.

Authorities began their inquiry after Nancy failed to attend Sunday church services, prompting a welfare check at her home. What deputies discovered quickly escalated concerns. According to Pima County Sheriff Chris Nanos, the residence is being processed as a crime scene due to signs of forced entry and evidence suggesting a struggle. The presence of a blood trail near the front entrance significantly heightened fears that Nancy did not leave voluntarily.